Inhibition of inhaled metabisulphite‐induced bronchoconstriction by inhaled frusemide and ipratropium bromide.
نویسندگان
چکیده
منابع مشابه
Effects of Inhaled Albuterol and Ipratropium Bromide
Study objective: Systemic administration of P-agonist and anticholinergic drugs markedly impair normal autonomic heart rate control. The purpose of this study was to quantify and compare the effects of therapeutic doses of inhaled albuterol and ipratropium on autonomic control of the cardiovascular system. Design: Randomized, double-blind, placebo-controlled, crossover design study. Setting: Te...
متن کاملProtective effects of inhaled ipratropium bromide on bronchoconstriction induced by adenosine and methacholine in asthma.
Although adenosine-induced bronchoconstriction is mainly due to mast cell mediator release, vagal reflexes have also been implicated in this response. We have investigated the effect of a specific muscarinic-receptor antagonist, ipratropium bromide, on methacholine- and adenosine-induced bronchoconstriction in a randomized, placebo-controlled, double-blind study of 12 asthmatic subjects. Airway...
متن کاملInhibition of adenosine 5'-monophosphate- and methacholine-induced bronchoconstriction in asthma by inhaled frusemide.
Recent studies have shown that inhaled frusemide exerts a protective effect against various bronchoconstrictor stimuli in asthma including exercise, fog and allergen. Since mast cell activation seems to be a component of bronchoconstriction by these stimuli it is possible that inhibition of mediator release accounts for some or all of the inhibitory effects of frusemide in asthma. Since inhaled...
متن کاملInhaled frusemide and exercise-induced bronchoconstriction in children with asthma.
BACKGROUND Nebulised frusemide has been shown to be protective against bronchoconstricting stimuli in adult asthmatic subjects and against cold air challenge in children. Animal studies suggest that inhaled frusemide may be more effective in the young. METHODS A double blind placebo, controlled, crossover study on the effect on exercise of pretreatment with frusemide (20 mg) from a metered do...
متن کاملBronchodilator effect of inhaled ipratropium bromide in wheezy toddlers.
smoking mothers are thinner and their babies are thinner too, but even accepting the limitations of correction for this effect, the growth-retarding effect of smoking on the fetus is hardly affected by this correction. A similar conclusion was derived from Cardiff Birth Survey data, in a community study on smoking and pregnancy.8 We postulate from our data and from other data already reported, ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1992
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.1992.tb04110.x